Software


SetTest
It provides cumulative distribution function (CDF), quantile, p-value, statistical power calculator and random number generator for a collection of group-testing procedures, including the Higher Criticism tests, the one-sided Kolmogorov-Smirnov tests, the one-sided Berk-Jones tests, the one-sided phi-divergence tests.

doi:10.1109/TSP.2020.2967179.

TFisher
It provides the cumulative distribution function (CDF), quantile, and statistical power calculator for a collection of thresholding Fisher’s p-value combination methods, including Fisher’s p-value combination method, truncated product method and, in particular, soft-thresholding Fisher’s p-value combination method. The p-value calculator for the omnibus version of these tests are also included.

doi:10.1214/19-AOAS1302.

CKAT
Composite Kernel Association Test (CKAT) is a flexible and robust kernel machine based approach to jointly test the genetic main effect and gene-treatment interaction effect for a set of single-nucleotide polymorphisms (SNPs) in pharmacogenetics (PGx) assessments embedded within randomized clinical trials.

doi:10.1093/bioinformatics/btaa125.

Qapprox
Calculates the right-tail probability of quadratic forms of Gaussian variables using the skewness-kurtosis ratio matching method, modified Liu-Tang-Zhang method and Satterthwaite-Welch method.

doi:10.1080/10618600.2021.2000423.

CauchyCP
An omnibus test of change-point Cox regression models to improve the statistical power of detecting signals of non-proportional hazards patterns.

doi:10.1177/09622802211037076.

GFisher
Accurate and computationally efficient p-value calculation for a general family of Fisher type aggregation statistics (GFisher).

doi:10.1111/biom.13634.

cwot
A flexible and robust joint test of the single nucleotide polymorphism (SNP) main effect and genotype-by-treatment interaction effect for continuous and binary endpoints.

doi:10.1093/bioinformatics/btac834.