Publications (Google Scholar)

* corresponding author; † equal contribution.

Study duration prediction for clinical trials with time-to-event endpoints using mixture distributions accounting for heterogeneous population
Hong Zhang*, Jie Pu, Shibing Deng, Satrajit Roychoudhury, Haitao Chu, Douglas Robinson.
Submitted. (2024+), arXiv:2401.00540.

Signal-noise ratio of genetic associations and statistical power of SNP-set tests
Hong Zhang, Ming Liu, Jiashun Jin, Zheyang Wu.
Annals of Applied Statistics. (2023), doi:10.1214/22-AOAS1725.

AWOT and CWOT for genotype and genotype by treatment interaction joint analysis in pharmacogenetics GWAS
Hong Zhang, Devan V. Mehrotra, Judong Shen.
Bioinformatics. (2023), doi:10.1093/bioinformatics/btac834.

Simultaneous detection of novel genes and SNPs by adaptive p-value combination
Xiaohui Chen, Hong Zhang, Ming Liu, Hong-Wen Deng, Zheyang Wu.
Frontiers in Genetics. (2022), doi:10.3389/fgene.2022.1009428.

Pharmacogenomics polygenic risk score for drug response prediction using PRS-PGx methods
Song Zhai†, Hong Zhang†, Devan V. Mehrotra, Judong Shen.
Nature Communications. (2022), doi:10.1038/s41467-022-32407-9.

A statistical perspective on baseline adjustment in pharmacogenomic genome-wide association studies of quantitative change
Hong Zhang, Aparna Chhibber, Peter M. Shaw, Devan V. Mehrotra, Judong Shen.
npj Genomic Medicine. (2022), doi:10.1038/s41525-022-00303-2.

The generalized Fisher’s combination and accurate p-value calculation under dependence
Hong Zhang, Zheyang Wu.
Biometrics. (2022), doi:10.1111/biom.13634. arXiv:2003.01286.

Germline HLA landscape does not predict efficacy of pembrolizumab monotherapy across solid tumor types
Aparna Chhibber†, Lingkang Huang†, Hong Zhang†, Jialin Xu, Razvan Cristescu, Xiaoqiao Liu, Devan V. Mehrotra, Judong Shen, Peter M. Shaw, Matthew D. Hellmann, Alexandra Snyder.
Immunity. (2022), doi:10.1016/j.immuni.2021.12.006.

A fast and accurate approximation to the distributions of quadratic forms of Gaussian variables
Hong Zhang*, Judong Shen, Zheyang Wu.
Journal of Computational and Graphical Statistics. (2021), doi:10.1080/10618600.2021.2000423. arXiv:2005.00905.

The general goodness-of-fit tests for correlated data
Hong Zhang, Zheyang Wu.
Computational Statistics & Data Analysis. (2021), doi:10.1016/j.csda.2021.107379. arXiv:1806.03668.

CauchyCP: a powerful test under non-proportional hazards using Cauchy combination of change-point Cox regressions
Hong Zhang*, Qing Li, Devan V. Mehrotra, Judong Shen.
Statistical Methods in Medical Research. (2021), doi:10.1177/09622802211037076. arXiv:2101.00059.

Distributions and statistical power of optimal signal detection methods in finite samples
Hong Zhang, Jiashun Jin and Zheyang Wu.
IEEE Transactions on Signal Processing. vol. 68 (2020), pp.1021-1033, doi:10.1109/TSP.2020.2967179. arXiv:1702.07082.

TFisher: A powerful truncation and weighting procedure for combining p-Values
Hong Zhang, Tiejun Tong, John Landers and Zheyang Wu.
Annals of Applied Statistics. vol. 14, no. 1 (2020), pp.178-201, doi:10.1214/19-AOAS1302. arXiv:1801.04309.

Composite kernel association test (CKAT) for SNP-set joint analysis of genotype and genotype-by-treatment interaction in pharmacogenetics studies
Hong Zhang, Ni Zhao, Devan Mehrotra and Judong Shen.
Bioinformatics. vol. 36, no. 10 (2020), pp.3162-3168, doi:10.1093/bioinformatics/btaa125.

Multi-trait analysis of rare-variant association summary statistics using MTAR
Lan Luo, Judong Shen, Hong Zhang, Aparna Chhibber, Devan Mehrotra and Zheng-zheng Tang.
Nature Communications. 11:2850 (2020), doi:10.1038/s41467-020-16591-0.

Releasing Wolbachia-infected Aedes aegypti to prevent the spread of dengue virus: a mathematical study
Hong Zhang, Roger Lui.
Infectious Disease Modelling. vol. 5 (2020), pp.142-160, doi:10.1016/j.idm.2019.12.004.